Library Browser
It should also be noted that no attempt has been made to produce contigs or consensus sequences. There are several reasons why the sequences of a set may not actually form a single contig. For example, all of the splicing variants for a gene are put into the same set. Moreover, EST-containing sets often contain 5 and 3 reads from the same cDNA clone, but these sequences do not always overlap.
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A representation of the UniGene datasets is available byftp
Boguski MS, Schuler ESTablishing a human transcript map. Nature Genetics 10: 369-371; 1995.
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Wheeler DL, et al. Database Resources of the National Center for Biotechnology. Nucl Acids Res 31:28-33;2003.
HomoloGene
However, it should be noted that the procedures for automated sequence clustering are still under development and the results may change from time to time as improvements are made. Feedback from users has been especially useful in identifying problems and we encourage you to report any problems you encounter.
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In addition to sequences of well-characterized genes, hundreds of thousands novel expressed sequence tag (EST) sequences have been included. Consequently, the collection may be of use to the community as a resource for gene discovery. UniGene has also been used by experimentalists to select reagents for gene mapping projects and large-scale expression analysis.
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Schuler . Pieces of the puzzle: expressed sequence tags and the catalog of human genes. J Mol Med 75:694-698; 1997.
UniGene Tumor vascular pelota,XGC
Finding cDNAs
EST
Each UniGene entry is a set of transcript sequences that appear to come from the same transcription locus (gene or expressed pseudogene), together with information on protein similarities, gene expression, cDNA clone reagents, and genomic location.
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DDD
UniGene ReferencesPontius JU, Wagner L, Schuler . UniGene: a unified view of the transcriptome. In: The NCBI Handbook. Bethesda (MD): National Center for Biotechnology Information; 2003.
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Gene
The cutoff date is the modification date of the most recent sequence included in a released UniGene dataset. In order to keep ancillary information such as gene namesTumor vascular pelota and reported protein alignments timely, UniGene releases are generated even when there is no new sequence data for an organism.UniGene Tumor vascular pelota New UniGene builds are announced to theUniGene build RSS
